About Us

Consultant Oncoloplastic Reconstructive, Aesthetic & Cosmetic Breast Surgeon MD, Dip, MRCS, AFRCS, FRCS(Ed) FRCS(Eng)

Mr. Kasem

He had his training and experience within the Oncoplastic Unit at the Princess Royal University Hospital. Mr Kasem spent 18 months as part-time secondment with the oncoplastic breast surgery team at the Royal Marsden Hospital. He joined South-East London Breast Cancer Screening at the King’s College University Hospital and the oncoplastic surgery team at St Thomas’ Hospital to perform the breast oncology procedures for breast cancer patients. Mr Kasem has been to many international breast cancer surgery and cosmetic breast surgery centres participating in breast cancer surgery, breast reconstruction and aesthetic cosmetic breast surgery master-classes and workshops. This has helped in mastering and refining his breast cancer surgery, breast reconstruction, aesthetic cosmetic breast surgery and oncoplastic breast skills. The surgical experience and training at these top different breast surgery centres have given Mr Kasem the golden opportunity to gain high expertise and skills in breast cancer surgery, breast reconstruction and aesthetic cosmetic breast surgery. His breast oncoplastic and cosmetic breast skills include primary breast cancer surgery, breast reconstruction surgery, breast augmentation, breast reduction, breast mastopexy (uplift), breast lipomodelling and lipofilling with fat grafting, immediate and delayed breast reconstruction and nipple reconstruction. Mr Kasem has been to the European Institute of Oncology in Milan and many international breast surgery centres to expand his skills of oncoplastic breast surgery. Mr Kasem is on the specialist GMC register as an accredited consultant surgeon. Mr Kasem is one of the first certified cosmetic surgeons by the Royal College of Surgeons of England in the United Kingdom.

Personal profile

Mr Kasem is an experienced oncoplastic breast surgeon with a specialist expertise in one stop rapid assessment for breast lumps, different breast symptoms, breast screening, family history risk assessment and state of art management for both benign breast disease and breast cancer. Mr Kasem works within a dedicated multidisciplinary team to provide the best holistic personal care. Mr Kasem is working as a Consultant Oncoplastic Breast Surgeon with a special interest in breast cancer surgery, breast reconstruction surgery and breast aesthetic surgery. He is an Oncoplasti Breast Consultant Surgeon at King’s College Hospital NHS Trust.

Training and experience:

Professional Membership:

British Association of Surgical Oncology (BASO) Association of Breast Surgeons (ABS) Royal College of Surgeons of England Royal College of Surgeons of Edinburgh British Medical Association Hospital Consultants and Specialists Association

Publications:

Mr Kasem has published many original articles in peer-review journals covering different hot topics of breast cancer surgery, breast cancer management, breast reconstruction surgery and aesthetic cosmetic breast surgery:
Can Complete Axillary Node Dissection Be Safely Omitted in Patients with Early Breast Cancer When the Sentinel Node Biopsy Is Positive for Malignancy? An Update for Clinical Practice. In Vivo. 2018 Nov-Dec;32(6):1477-1480. doi: 10.21873/invivo.11402.

The Impact of EndoPredict Clinical Score on Chemotherapy Recommendations in Women with Invasive ER+/HER2- Breast Cancer Stratified as Having Moderate or Poor Prognosis by Nottingham Prognostic Index. Anticancer Res. 2018 Aug;38(8):4747-4752. doi: 10.21873/anticanres.12782

Do online prognostication tools represent a valid alternative to genomic profiling in the context of adjuvant treatment of early breast cancer? A systematic review of the literature. Am J Surg. 2018 Jan;215(1):171-178. doi: 10.1016/j.amjsurg.2017.05.006. Epub 2017 Jun 3. Review

Is sentinel lymph node biopsy indicated in patients with a diagnosis of ductal carcinoma in situ? A systematic literature review and meta-analysis.
Am J Surg. 2017 Jan;213(1):171-180. doi: 10.1016/j.amjsurg.2016.04.019. Epub 2016 Sep 6. Review. PMID: 27773373

Is sentinel lymph node biopsy a viable alternative to complete axillary dissection following neoadjuvant chemotherapy in women with node-positive breast cancer at diagnosis? An updated meta-analysis involving 3,398 patients. Am J Surg. 2016 Nov;212(5):969-981. doi: 10.1016/j.amjsurg.2016.07.018. Epub 2016 Aug 16. Review.
PMID: 27671032

Improvement of survival with postmastectomy radiotherapy in patients with 1-3 positive axillary lymph nodes: A systematic review and meta-analysis of the current literature. Mol Clin Oncol. 2016 Oct;5(4):429-436. Epub 2016 Aug 1. PMID: 27699038
Oncological Safety of Lipofilling in Patients with Breast Cancer: A Meta-analysis and Update on Clinical Practice. Anticancer Res. 2016 Sep;36(9):4521-8. Review.

Does fat transfer increase the risk of breast cancer recurrence? A meta-analysis involving 2382 patients. Abstract. Cancer Research. Abstract P3-14-03: DOI: 10.1158/1538-7445.SABCS16-P3-14-03 Published February 2017

The role of sentinel lymph node biopsy in patients with ductal carcinoma in situ. An updated meta-analysis involving 9803 patients. Abstract. Cancer Research. DOI: 10.1158/1538-7445.SABCS16-P3-17-08 Published February 2017
Oncological safety of lipofilling in patients with breast cancer: A meta-analysis and update to clinical practice. Abstract. European Journal of Surgical Oncology. Volume 42, Issue 11, Page S217

The role of sentinel lymph node biopsy in patients with ductal carcinoma in situ. An updated meta-analysis involving 9803 patients. Abstract. European Journal of Surgical Oncology, Vol. 42, Issue 11, S24

When the breast surgeons take the lead in genetic testing, how satisfied are the patients? Abstract. European Journal of Surgical Oncology, Vol. 42, Issue 11, S246

In the era of conservative surgery, can patients presenting with node positive breast cancer be spared axillary node dissection post neoadjuvant chemotherapy? A meta-analysis and review of literature. Abstract. European Journal of Surgical Oncology, Vol. 42, Issue 11, S245

Nipple-sparing mastectomy using a hemi-periareolar incision with or without minimal medial-lateral extensions; clinical outcome and patient satisfaction: a single centre prospective observational study. Am J Surg. 2016 Jul 21. pii: S0002-9610(16)30359-2. doi: 10.1016/j.amjsurg.2016.04.016. [Epub ahead of print] PMID: 27523925

The Oncological Safety of Nipple-Sparing Mastectomy: A Systematic Review of the Literature with a Pooled Analysis of 12,358 Procedures. Arch Plast Surg. 2016 Jul;43(4):328-38. doi: 10.5999/aps.2016.43.4.328. Epub 2016 Jul 20. Review.

Clinical outcome and patient satisfaction with the use of bovine-derived acellular dermal matrix (SurgiMend™) in implant based immediate reconstruction following skin sparing mastectomy: A prospective observational study in a single centre. Surg Oncol. 2016 Jun;25(2):104-10. doi: 10.1016/j.suronc.2016.03.004.

Surgical treatment of the primary tumour improves the overall survival in patients with metastatic breast cancer: A systematic review and meta-analysis. Mol Clin Oncol. 2016 May;4(5):863-867. Epub 2016 Feb 16.

Biological and synthetic mesh use in breast reconstructive surgery: a literature review. World J Surg Oncol. 2016 Apr 21;14(1):121. doi:10.1186/s12957-016-0874-9.

Refining the Performance of Sentinel Lymph Node Biopsy Post-neoadjuvant Chemotherapy in Patients with Pathologically Proven Pre-treatment Node-positive Breast Cancer: An Update for Clinical Practice. Anticancer Res. 2016 Apr; 36(4):1461-71.

The impact of EpClin assay on treatment decision-making in women with estrogen receptor-positive, early breast cancer: The London Breast Institute experience. Abstract. European Journal of Surgical Oncology. Vol42, Issue 5, May 2016. S19. P029.
http://dx.doi.org/10.1016/j.ejso.2016.02.082

Clinical outcome and patient satisfaction with the use of bovine-derived acellular dermal matrix (Surgimend) in implant based immediate reconstruction following skin sparing mastectomy in the setting of radiotherapy: a prospective, observational study. Abstract. European Journal of Surgical Oncology. Vol42, Issue 5, May 2016. S46. P126. http://dx.doi.org/10.1016/j.ejso.2016.02.179

Is sentinel lymph node biopsy a viable alternative to complete axillary clearance following neoadjuvant chemotherapy in women with node positive breast cancer at diagnosis? A meta-analysis. Abstract. European Journal of Surgical Oncology. Vol42, Issue 5, May 2016. S47. P130. http://dx.doi.org/10.1016/j.ejso.2016.02.183

Is the use of sentinel lymph node biopsy indicated in the setting of ductal carcinoma in situ? A meta-analysis. Abstract. European Journal of Surgical Oncology. Vol42, Issue 5, May 2016. S48. P131. http://dx.doi.org/10.1016/j.ejso.2016.02.184

UK national survey of management of breast lobular carcinoma in situ. Journal of Annals Royal College of Surgeon of England. 2015 Nov;97(8):574-7. doi: 10.1308/rcsann.2015.0037.

Clinical outcome and patient satisfaction with the use of bovine-derived acellular dermal matrix (SurgiMendTM) in implant based immediate reconstruction following skin sparing mastectomy: a prospective observational study in a single centre. Abstract. European Journal of Surgical Oncology. Vol41, Issue 11, Nov 2015. S268.24. http://dx.doi.org/10.1016/j.ejso.2015.08.055

Capsular contracture after breast augmentation: an update for clinical practice. European Journal of Surgical Oncology. Vol41, Issue 11, Nov 2015. S280. P44. http://dx.doi.org/10.1016/j.ejso.2015.08.149

Does postmastectomy radiotherapy improve survival in patients with 1-3 positive axillary lymph nodes? A systematic review and meta-analysis of the current literature. European Journal of Surgical Oncology. Vol41, Issue 11, Nov 2015. S279. P40. http://dx.doi.org/10.1016/j.ejso.2015.08.145

Does surgical treatment of the primary tumour improve the overall survival in patients with metastatic breast cancer? A systematic review and meta-analysis. European Journal of Surgical Oncology. Vol41, Issue 11, Nov 2015. S278. P36. http://dx.doi.org/10.1016/j.ejso.2015.08.141

Oncological safety of nipple sparing mastectomy: A systematic review of the literature with pooled analysis of 12358 procedures. European Journal of Surgical Oncology. Vol41, Issue 11, Nov 2015. S277. P29. http://dx.doi.org/10.1016/j.ejso.2015.08.134

An audit of a single practice of immediate and delayed breast reconstruction in a district general hospital. European Journal of Surgical Oncology. Vol41, Issue 11, Nov 2015. S277. P29. http://dx.doi.org/10.1016/j.ejso.2015.08.134
Multidisciplinary meeting and mastectomy making decisions. European Journal of Surgical Oncology. Vol41, Issue 11, Nov 2015. S276. P27. http://dx.doi.org/10.1016/j.ejso.2015.08.132

A systematic review of the oncological safety of breast lipo-filling. European Journal of Surgical Oncology. Vol41, Issue 11, Nov 2015. S276. P26. http://dx.doi.org/10.1016/j.ejso.2015.08.131

Capsular Contracture after Breast Augmentation: An Update for Clinical Practice. Arch Plast Surg. 2015 Sep;42(5):532-43. doi: 10.5999/aps.2015.42.5.532. Epub 2015 Sep 15

Lipofilling: a review of current practice. Arch Plast Surg. 2015 Mar;42(2):126-30. doi: 10.5999/aps.2015.42.2.126. Epub 2015 Mar 16

The clinical implications of poly implant prothèse breast implants: an overview. Arch Plast Surg. 2015 Jan;42(1):4-10. doi: 10.5999/aps.2015.42.1.4. Epub 2015 Jan 14.

Breast Lymphoma: A single-centre case series. Abstract. European Journal of Surgical Oncology. Vol.41, Issue 6, June 2015. S68 P149. http://dx.doi.org/10.1016/j.ejso.2015.03.187

The role of death-associated protein 3 in apoptosis, anoikis and human cancer. Cancer Cell Int. 2015 Apr 10;15:39. doi: 10.1186/s12935-015-0187-z. eCollection 2015.

Skin-Sparing Mastectomy and Breast Reconstruction: An Update for Clinical Practice. Journal of Cancer Therapy, March 2014, 5,264-280. First Author

National audit of management of breast lobular carcinoma in situ (LCIS). Abstract. European Journal of Surgical Surgery. Vol.40, Issue 5, May 2014. P601. Senior author.

Systematic literature review of breast lobular carcinoma in situ (LCIS). Abstract. European Journal of Surgical Surgery. Vol.40, Issue 5, May 2014. P 614. Senior author.

Evolving role of skin-sparing mastectomy. Editorial Article. World J Clin Oncol. May 10, 2014; 5(2): 33–35.

Audit of outcome following core biopsies grades as B3 – Is surgical excision biopsy justified? Abstract. European Journal of Surgical Oncology. Vol.39, Issue 5, May 2013. P107. Senior author

mRNA expression of DOK1-6 in human breast cancer. World J Clin Oncol. May 10, 2014; 5(2): 156–163.

Breast reconstruction using porcine acellular dermal matrix (Strattice) = Abstract. Oncoplastic Reconstruction Breast Surgery (ORBS) Meeting. Abstract Booklet.

mTORC1 and Rictor expression in human breast cancer: correlations with clinicopathological parameters and disease outcome. San Antonio Breast Cancer Symposium 2012; December 17, 2012; San Antonio, USA: Cancer Res; 2012. p. P1-04-09.

Evidence for anti-apoptosis function of GNB1 in human breast cancer. San Antonio Breast Cancer Symposium 2012; December 17, 2012; San Antonio, USA: Cancer Res; 2012. p. P1-04-08.

Contrasting correlation of Mtorc1 and Rictor with clinical pathological parameters in human cancer: A “Gas and Ped…” relationship? European Journal of Surgical Oncology. Vol.38, Issue 11, Nov 2012. P53.

A single institution experience with skin sparing mastectomy and immediate breast reconstruction. Original Article. Annals of The Royal college of Surgeons of England 2011; 93: 382-384

Bone Scan and Liver Ultrasound Scan in the Preoperative Staging for Primary Breast Cancer. Original Article. The Breast Journal, 2006; 12 (6), 544–548. First author

Preoperative staging for primary breast cancer. Abstract. British Journal of Surgery – Vol.92, Suppl 1, April 2005. P:15. First author

Mastectomy making decision multidisciplinary meeting (MDM) revisited. Abstract. European Journal of Surgical Oncology. Vol.31, Suppl 9, Nov 2006. S98. First author

Wire localisation for screen detected breast cancer. Abstract. European Journal of Surgical Oncology. Vol.32, Suppl.1, Nov 2006, S99 First author

Routine pre-operative staging for primary breast cancer: UK national audit and a local practice. Abstract. European Journal of Surgical Oncology. Vol.32, Suppl.1, Nov 2006, S86 First author

Ultrasound tumour measurements: potential for mismanagement in Primary Breast Cancer. Abstract. European Journal of Surgical Oncology. Vol.32, Suppl.1, Nov 2006, S98. Participating Author

Skin sparing mastectomy and immediate breast reconstruction: is it safe? Abstract. European Journal of Surgical Oncology. Vol.32, Suppl.1, Nov 2006, S89-S90. Participating Author

Upgrading of routine GP referrals to urgent by the breast care nurses avoids delay in diagnosis of breast cancer. Abstract. European Journal of Surgical Oncology. Vol.32, Suppl.1, Nov 2006, S90 Participating Author

National audit of preoperative staging for primary breast cancer. Abstract. European Journal of Surgical Oncology. Vol. 31, Suppl. 31, November 2005. P: 1090. First author.Mr Kasem has published many original articles in peer-review journals covering different hot topics of breast cancer surgery, breast cancer management, breast reconstruction surgery and aesthetic cosmetic breast surgery:
Can Complete Axillary Node Dissection Be Safely Omitted in Patients with Early Breast Cancer When the Sentinel Node Biopsy Is Positive for Malignancy? An Update for Clinical Practice. In Vivo. 2018 Nov-Dec;32(6):1477-1480. doi: 10.21873/invivo.11402.